Binding of Isaac: Rebirth Wiki is a FANDOM Games Community. sack, pouch, blue, purple, Tears gain a damage up and increase in size based on the distance they travel, The length of a normal room roughly gives +6 damage, but this can be higher with double rooms or Tiny Planet, This item synergises with beam items such as Brimstone and Tech, allowing them to do more damage the further away the enemy is, When used, removes one heart container and gives you 3 soul hearts, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, Blood Bag) it will be rerolled into a random Item Room item, Cannot remove Azazel's Brimstone laser, or The Lost's Holy Mantle, REPENTANCE - Full run reroll effects are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by blowing up 30 slot machines, * item room, treasure room, item room pool, dice pip, starting, pyramid, green, triange, When used, 'devolves' all enemies in the room which are currently alive into another weaker type of enemy, * item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban, When used, copies the effect of the card you are currently holding without consuming it, The charge time of this item depends on the quality of the card you're holding, Using this with the ? Manage all your favorite fandoms in one place! Carry them with you", "The walls will harden over time. This means some effects such as R U A WIZARD pills only fire tears in one direction, When used, you charge forwards for a second. A member of the Tulsa-based pop group Hanson said he feels a duty to share his "scary experience" with deep vein thrombosis while health officials in his home state work to promote awareness of the medical condition. now allows the player to influence the teleport direction (using the direction Isaac is moving upon activating the item), * item room, treasure room, item room pool, blue remote, robot, When used as the Keeper, one coin HP is restored, Has a chance to drop from the Super Lust miniboss fight, Item Pool: Item Room, Super Lust Miniboss, * item room, treasure room, item room pool, the lost item pool, maggy, starting, bomb beggar, green, dead, face, bobs curse, bob curse, Spawns 7 random coins around Isaac on the floor, * boss room pool, boss room item, dtQt, dtphase, crown, nocrown, yescrown, diana, ?, Satan and The Lamb as Tainted Cain, Spawns a sack at the start of each new floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Cain, Causes an Item Room and Shop to appear in Sheol, UNLOCK: Unlock this trinket by defeating Isaac, ?? Picking up Brimstone will multiply Isaac's current damage by 3. Taking it will cause Mom's Shadow to spawn and chase you. the lost item pool, white, A familiar that follows Isaac and can fire up and charge brimstone shots, exactly how the normal Brimstone item works but with less damage, Each laser deals 3 damage per tick, up to 8 times for a total of 31.5 damage, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, horns, baby, ?, Satan and The Lamb as Tainted Magdalene, The first time you pick this trinket up, the heart container will be filled. Each room is locked to a specific trinket effect, meaning if you exit and re-enter a room, that specific room will always have the same effect. orange, moms wig, Gives a chance to heal 1/2 a red heart every time the in-game timer hits a new minute, There are no restrictions on when the regeneration effect happens as long as the game is not paused, so you can simply afk and heal over time, It's possible to find this item by blowing up Polyps (the weird red rocks found in the Womb floors), * boss room pool, boss room item, the lost item pool, purple, red, lump, When you get hit, you will sometimes cause hearts to drop on the floor, The chance to drop hearts is affected by your luck stat and at +29 Luck it will activate 50% of the time, * boss room pool, boss room item, the lost item pool, plasters, white, Everytime a bomb explodes, it will release a circle of 10 tears outwards, much like the Tammy's Head effect, The tears from each bomb deal a flat 25 damage and are affected by any tear modifiers Isaac has, The tears caused by Sad Bombs are much larger and do a lot more damage than Isaac's normal tears, * boss rush pool, boss rush room, item room, treasure room, item room pool, crying, face, Isaac's tears now bounce off walls and objects in the environment, such as rocks and pots, Allows tears to hit the same enemy multiple times, If you also have Lost Contact, tears will bounce off enemy projectiles instead of being destroyed, UNLOCK: Unlock this item by beating Mom's heart 2 times, * item room, treasure room, item room pool, orange, brown, bottle, jar, As you hold down the fire button, shots will float in the same place until you release the fire key again, Allows you to store up a lot of tears in the air and release them all at once, When the tears are released, they will fire off in the direction that Isaac was originally facing when it was created, * anti gravity, item room, treasure room, item room pool, anti gravity, atom, nucleus, All explosions now heal Isaac for 0.5 red hearts instead of hurting him, REPENTANCE - Pyromaniac now grants Isaac immunity to fire, but no longer protects against stomps or shockwaves. ), Keeps the chance at 100% even after entering and leaving the angel room, meaning the door will not close after visiting, Makes it impossible to find Devil Rooms again, unless you find a way to remove or reroll this item away, or find the Duality item, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Maggy, A sack familiar that drops a sack every 5 or 6 rooms cleared (alternates between 5 and 6), UNLOCK: Unlock this item by defeating Greedier Mode as Cain, * back in black, ac/dc, bag, brown, pouch, pocket, bulge, Gives you an extra heart container for every 25 coins you are currently holding, up to a maximum of 4 extra HP at 99 coins held, If your coin counter goes below the required amount for a heart container, you will lose it again, This item works for the Keeper, allowing him to exceed his usual 2 health containers, However, if Keeper drops to under 2 health coins as a result of Greed's Gullet, he is unable to use a HP Up to increase his health back to 2, and has to regain the lost coins to do so, UNLOCK: Unlock this item by beating Challenge #35 (Pong), *, dollar, cash, sack, bag, pouch, greeds gullet, greed gullet, Gives you a random chance while firing tears to also fire a creep shot, which deals double your tear damage and places white creep on the floor infront of you that slows enemies down if they walk through it, Unlike some similar tear effects, your luck stat does not alter the chance for this effect to activate, A creep shot is also fired in a random direction after taking damage, While firing tears you have a 5% chance to fire a void tear. When an enemy takes damage from an enemy projectile, it will attempt to target the enemy that fired it, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Judas, Item Pool: Item Room, Greed Mode Item Room, Devil Room, Greed Mode Devil Room, Zodiac will give you a random zodiac item effect that changes after every floor, Possible item effects include: Taurus, Aries, Cancer, Leo, Virgo, Libra, Scorpio, Sagittarius, Capricorn, Aquarius, Gemini or Pisces, UNLOCK: Unlock this item by beating Greed Mode with The Lost, Tears now have a random chance to apply a poison effect, dealing damage equal to your tears each tick, for 2 ticks, Isaac now deals poison damage on contact with enemies similar to The Virus item (Damage over time 4 or 6 per tick), Enemies that were poisoned by contact damage have a 20% chance to drop a black sin heart when killed. UNLOCK: Unlock this item by defeating Delirium as Tainted Bethany, When used, removes half a heart of health and creates a clot familiar, Clot familiars follow Isaac's exact movements including flight, firing tears and tear effects, Holding down the swap button will cause all your clots to stay in place, Works differently as Tainted Eve - instead clots are created by firing for 2 seconds, down to a minimum of half a red heart. Blood clotting becomes a problem when it blocks your blood . achievement (collect 50 items in a single run), X-Lax - Spawns a pool of slippery brown creep beneath Isaac, Experimental Pill - Increases one random stat and decreases another random stat. Acquire Blood Clot 10 times. Items * secret room pool, item room, treasure room, item room pool, 25, grey, gray, silver, devil pool, devil room pool, devil deal, Converts most negative pills into their positive counterparts, e.g. UNLOCK: Unlock this trinket by collecting three of the following in the same run: Magic 8 Ball, Tiny Planet, Crystal Ball, Star of Bethlehem or any of the Astrology-related items (e.g. The first piece drops by beating the first floor boss within 1 minute then bombing the shadow in the first room. Counts as 1 of 3 evil items needed towards the Leviathan transformation. Yeah I saw one of those rooms on the map too. Unlike the regular D6, rerolled items can pick from any item pool, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Eden, When used, Isaac dies and becomes The Lost for the current room. This includes key blocks and secret room doors, +1.0 Damage Up, but each rock tear has a random damage modifier that can go up or down (x0.5 to x2), Allows Isaac to charge by double tapping the same direction, dealing damage to any enemies caught, You are invincible while charging (doesn't include self-damage like Blood Donation machines), The dash deals x4 your current tear damage + 8, Doesn't have to be in a straight line, you can hold another button to curve it, Has a 3 second cooldown before it can be used again, While not moving your speed rapidly increases up to a bonus of +0.5, While you have this +0.5 bonus, moving will cause Isaac to fart around the room, spawning poison gas clouds, The farts stop spawning once you reach your regular movement speed, Poison deals damage equal to half your tears per tick, Isaac is immune to Poison from enemies, such as Gasbag, Gives you a wide circle halo which grants 7 orbital tears upon entering a new room, The tears orbit for 13 seconds before dropping off, Has a chance to absorb any enemy tears and add them to the orbiting tears. white, brown, underwear, moms bra, mom bra, Causes an explosion near Isaac which takes away half a heart and does 40 damage all enemies in close proximity, REPENTANCE - Kamikaze now has increased blast damage and radius. Following the path takes you to an abandoned mineshaft, which leads you to a pedestal with the Knife Piece. Trinkets UNLOCK: Unlock this trinket by defeating Mother as Tainted Lost, Has a decent chance for Devil Deals to cost money instead of Health, The conversion rate is 1 heart container to 15 coins, Items can be on discount similar to the shop, making it 1 heart container = 7 coins instead, Can be dropped to disable this effect while in the room, UNLOCK: Unlock this trinket by defeating Isaac, ?? Item Pool Everything is sold for its shop price, e.g. Taking this item DOES count as a devil deal, preventing future angel rooms. The barrage size is 8 without any multi-shot effect. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, And just to be clear in case someone doesn't understand: it was a few days after Rebirth release. Your doctor will likely perform a physical examination, and you may undergo a venous . Using it with less than 5 coins does nothing, UNLOCK: Unlock this item by collecting 99 coins then spending all of them in the same run, Item Pool: Item Room, Greed Mode Item Room, Upon use, grants use of Brimstone for the current room, If used twice in the same room, the brimstone laser becomes massive and deals +1.8 more damage, Using it more than twice in the same room will give a damage increase each time. Item Icon Endings. This tear turns enemies to gold for a few seconds and causes them to drop 1-4 coins if killed while golden (similar to the Midas' Touch item), When the Midas Touch tear effect triggers, it will remove 1 coin from your current total, The golden tear deals double your tear damage, The effect can still trigger even if you have no held coins, UNLOCK: Unlock this item by defeating Greedier Mode with Keeper, Doubles the effect of most tarot cards. Fire Dips burn enemies and leave a fire behind on death. Objects purple, An orbiting fly which deals 2 contact damage per tick to enemies, * item room, treasure room, item room pool, blue, Has a chance to drop from the Super Gluttony miniboss fight, Item Pool: Item Room, Super Gluttony Miniboss, * item room, treasure room, item room pool, the lost item pool, white, grey, gray, tub, Allows Isaac to fly while the Pony is held, Sets your speed stat to 1.5 if it isn't already that high, When the active attack is used, Isaac will dash across the screen dealing scaling contact damage to anything he hits, Drops from the Headless Horseman boss fight, REPENTANCE - A Pony's charge time has been reduced to 2 (from 4). Update 1.7.9b (9th Dec) changes have been added to the site, When used, copies the effect of the Rune or Soul stone you are holding (like the Blank Card), Drops a random rune on the floor when picked up. Attributes Haemolacria tear appearance with Dr. Fetus. "I am very excited to get out on the road," says the 27-year . at base damage of 3.5, that's 45 damage), Self-inflicted damage such as Blood Donation machines don't trigger this effect, Isaac's bombs will now explode in a large cross-shaped pattern (roughly 5 bombs explosions wide), Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar. (Does not roll your devil deal items), 5 Dot - Reroll and restart the current floor (Forget Me Now effect), 6 Dot - Reroll all of your items and all the pickups on the entire floor (Combined 1 + 3 + 4 rooms), The same order as the in-game collection page. a bomb can become a troll bomb, or a dropped coin can become a dime, UNLOCK: Unlock this trinket by defeating Isaac, ?? Brimstone Bombs: Brimstone beams will shoot out upon exploding. The laser hits up to 13 times if an enemy stays inside it for the duration, Has a chance to drop from the Envy and Super Envy miniboss fights, Item Pool: Item Room, Envy Miniboss, Super Envy Miniboss, * item room, treasure room, item room pool, red, lips, white, eyes, UNLOCK: Unlock this item by beating the Basement 40 times and defeating the Steven boss, *, black, white, face, eyes, mouth, golden chest pool, +10% chance of a devil/angel room opening while held, A second Pentagram will give an extra +5% chance, Counts as 1 of 3 evil items needed towards the Leviathan transformation, Item Pool: Boss Room, Curse Room, Devil Room, Demon Beggar, Crane Game, * curse room pool, devil pool, devil room pool, devil deal, boss room pool, boss room item, * boss room pool, boss room item, mr. squeezy, mr squeezy, cobaltstreak, white, brown, red, bow, * boss room pool, boss room item, purple, carton, grape drank, When picked up, spawns 1 red heart, 1 key, 1 bomb, 1 coin, 1 card/rune, 1 pill and 1 trinket, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, brown, orange, cardboard, Doubles the yield of hearts, coins, bombs and keys that spawn from non-red chests, Item Pool: Shop, Challenge Room, Key Beggar, Mom's Chest, * key master pool, key beggar pool, key judgement pool, , dungeon room, blood challenge room, arena pool, shop room pool, shop item pool, golden, horns, moms key, mom key, Tears have a random chance to charm enemies, Charmed enemies will prioritize attacking other enemies in the room, otherwise they will still attack Isaac, The chance to charm enemies is affected by your luck stat and at +27 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, Lasers sound deeper and bassier. grey, gray, green, mouth, bobs rotten head, bob rotten head, Teleports Isaac to a random location on the map, Can't be used to teleport to the I AM ERROR room, REPENTANCE - Teleport! Each time you destroy a poop, this item will spawn 1-4 friendly Dip familiars that follow you, block shots and attack nearby enemies, Different poop types will spawn different types of Dip, each with their own effect, Golden poop dips can petrify enemies, turning them to gold for a few seconds. The damage bonus is unaffected by both positive and negative damage multipliers. you could find a caves boss in the basement. The copy of you (enemy in the womb) will always shoot. Isaac appears demonic with large curved horns and an angry expression. Azazel: Overrides Azazel's Brimstone. Toxic Dips release a poison cloud when they move/die. Also works for opening Spiked Chests and Mimic Chests without taking damage, When used, this item restarts the game and places you back on the first floor with all your currently collected items, similar to doing a Victory Lap, Allows angel rooms to be found in the new run if a devil deal was taken in the first run, In Greed Mode and while playing as Tainted Keeper, this item costs 99 coins instead of 15. Chapters ?, Satan and The Lamb as Tainted Samson, When taking damage you have a chance to explode and deal 185 damage to all enemies around you (Same damage as a Mr. Mega bomb), UNLOCK: Unlock this trinket by defeating Mother as Tainted Samson, Familiars follow Isaac's exact movements, (similar to how Jacob & Esau work) instead of following loosely like they usually do, Holding the drop button (Ctrl on Steam version) causes them to stop moving, Doesn't affect some familiars with specific movement patterns, e.g. The main purpose of the Cracked Key is to unlock Tainted character in the Home floor without needing to find the Red Key. Recharge time: Starts at 1 second, increasing by every time you use it. It can only be fired after a short charge-up period (approximately 1-2 seconds until Isaac's head begins flashing red). ?, Soul of the Lost, 4 rooms: Rune of Ehwaz, Rune of Perthro, Black Rune, Soul of Isaac, Soul of Eve, Soul of Eden, Soul of the Forgotten, Soul of Jacob and Esau, 6 rooms: Rune of Dagaz, Soul of Samson, Soul of Azazel, Soul of Apollyon, Soul of Bethany, 12 rooms: Rune of Jera, Soul of Lilith, Soul of the Keeper, Tears have a chance to fire a fungus tear that sticks to enemies. The Forgotten - Your Soul is now unchained and free to move. The chance for a Red Room to unlock increases as you pick up more Crystal Keys. The room doors will open if only frozen enemies remain, UNLOCK: Unlock this trinket by defeating challenge #41 (Pica Run), Every time you kill an enemy you get an invincibility shield for 1 second, While shielded, each enemy killed adds +1 seconds to the duration, UNLOCK: Unlock this trinket by defeating challenge #37 (Bloody Mary), * item room, treasure room, item room pool, green, cry, plant, Tears now shoot three at a time (Triple Shot). This mechanic is very useful on Greed and Greedier modes, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper, *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health, UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve, When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+1.5 Range Up + red creep trail) and a Cube of Meat, The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent, Only works for red hearts and has no effect when used if you only have soul/black hearts, Has no recharge time and can be used as often as you like, It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat, When used, this item gives you the effect of a random item for the rest of the room, Using this item multiple times in the same room will replace the previous item's effect with a new one, Certain items can be activated with this item which have unexpected effects and many items will do nothing, Items do not grant consumable drops which would normally occur when that item is picked up, Most flight-granting items have cosmetic effects only, and will not allow you to fly, Items that usually give HP up will not give extra health when gained from Metronome, UNLOCK: Unlock this item by defeating Greedier Mode with Eden, This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use, Charge time scales based on the chosen dice, updating every time you use it, Possible dice include: D1, D4, D6, D8, D10, D12, D20, D100. devil room pool, devil deal, grey, gray, hood, Isaac now has a small chance to create friendly attack spiders everytime he fires a tear, Can create up to a maximum of 5 spiders in the room at one time, The Hive Mind item allows Mom's Wig to spawn a maximum of 10 spiders at once, and increases their damage, The chance to create a spider is affected by your luck stat and at +10 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, UNLOCK: Unlock this item by defeating Mother in the Corpse II as ??? Rooms slow, shrink, fear), Spider Mod will also randomly drop battery consumables or blue spiders when a room is completed, For the sake of simplicity for players, all damage values displayed are multiplied by 10 and rounded to the nearest number, This item is a reference to Spider853, creator of Spidermod for the original game and one of the lead developers that worked on Rebirth and its DLCs, *, robot, red, grey, gray, silver, metal, antenna, A familiar that follows Isaac and blocks tears, If a tear hits Farting Baby, there is a 10% chance for it to fart, with 3 possible effects: Charm, Poison or Knock back, Charm deals 5 damage. And chase you cloud when they move/die price, e.g the Cracked Key is to unlock increases you... Brimstone beams will shoot out upon exploding pedestal with the Knife piece mineshaft, which leads you an. Burn enemies and leave a fire behind on death 1 second, increasing by every you! 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